Description, Causes and Risk Factors:
Also called as tsutsugamushi disease.
An acute infectious disease caused by Rickettsia tsutsugamushi and transmitted by Trombicula akamushi and T. deliensis that occurs in harvesters of hemp in some parts of Japan; characterized by fever, painful swelling of the lymphatic glands, a small blackish scab on the genitals, neck, or axilla, and an eruption of large dark red papules.
Alternative Names: Island disease, shimamushi disease, flood fever, inundation fever, island fever, Japanese river fever, kedani fever, tsutsugamushi fever, mite typhus, scrub typhus, and tropical typhus.
An infection caused by Orientia tsutsugamushi - a small intracellular bacterium related to the family of Rickettsiaceae - the organism is classified on its own and not with other rickettsiaceae as it has differences in genes and cell wall structure. The name scrub typhus was applied after discovery of increased frequency of the disease in scrub or wasteland areas.
Orientia tsutsugamushi is transmitted by the ovaries of trombiculid mites. The offspring mites or larvae are then infected and these are known as "chiggers". These mites then pass the infection to humans by feeding on the fluid in skin cells.
Infection with scrub typhus is most often self-limiting but can occasionally be severe and even fatal.
The early clinical course of Akamushi disease is marked by a gradual rise of the body temperature and swelling of the adjacent lymph nodes. The incubation period is about eight days. The fever, which is usually 38-39 C in the early stage, may rise to 40 C or ever higher, and usually last three or four weeks. In bad cases a fatal results follows about tend days after the onset. The mortality of the disease is approximately forty percent.
PCR: Some studies have used PCR (polymerase chain reaction) on specimens obtained from eschars. This involves obtaining a small piece of the eschar and then amplifying the DNA to look for the genetic sequence of scrub typhus.
Antibiotics: Doxycycline orally or chloramphenicol in more severe cases. Azithromycin has been used in resistant cases and may be better than doxycycline - especially in children and pregnant women
DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.
Recent research suggests that a handful of nuts, such as Brazil nut, cashew or pistachios, may reduce the risk of a heart attack or stroke by 33% in people with diabetes. Having performed analysis of the received data, the researchers discovered that people who ate an...
A new study from the US suggests that middle-aged men who are able to do 40 push-ups and more in one session have lower risk of cardiovascular disease than men who can do fewer than 10 push-ups. For a retrospective longitudinal study from 2000 to 2010, 1,104...
In childhood, many of us dreamed of learning to jump high. Now, after years, it became easier - Kangoo Jumps has appeared. This is one of the relatively new, but quickly gaining popularity types of fitness training. There are several advantages of jumpers. ...read more
It is time for us to find the solution how to deal with extra weight which is coming with Christmas and New Year’s celebrations because 2018 is almost over and 2019 is getting closer. The main aim is obviously staying in shape and today will find an effective way to...read more
We know that moderate exercise strengthens our health and makes us more beautiful. But few know about the importance of doing sports as psychotherapy. And, nevertheless, physical loads can save from depressions, reduce anxiety, relieve from professional burnout,...read more