Anhydrous caffeine

Anhydrous caffeineAnhydrous caffeine (a pure powder caffeine or a pill) is a dehydrated caffeine, with no more than 0.5% of hydration in it.


Caffeine is the most consumed substance which stimulates the central nervous system. The consumption of caffeine may alleviate fatigue, increase the feeling of wakefulness and improve concentration and focusing. However, caffeine anhydrous is used mainly to lose weight

It was estimated that 1 teaspoon of anhydrous caffeine causes the same effect as approximately 28 cups of regular coffee. That is why the consumption of pure caffeine powder may be even life-threatening and side effects are more likely to occur in those who use caffeine anhydrous.  
According to the researches 5 grams of caffeine may cause the death of the consumer.


Anhydrous caffeine is an odorless dry white powder with a bitter taste.



Caffeine anhydrous may be sold as a soluble powder or a pill (No-Doze).


Mechanism of action

Caffeine increases the levels of epinephrine and norepinephrine in the blood. These substances stimulate the fat dissolution.
At the same time caffeine stimulates dieresis and helps to excrete excessive fluid.

Related: Drinking Coffee Could Help with Losing Weight and Exercise More


It is believed that caffeine powder is helpful as a substance to burn fat and at the same time to reduce the muscle pain after the physical workout.

During its metabolism in the liver caffeine produces three active metabolites, each of them provides a special effect. These are paraxanthine, theobromine and theophiline.

Paraxanthine (1,7-dimethylxanthine) increases cAMP and PKA and that way the lipids are dissolved.

Theobromine (Xantheose) provides vasodilatation . This effect increases the blood supply to the internal organs and the brain.

Theophilline is an energy booster.



It is recommended to use not more than 200 mg of caffeine per day, although some permit to use up to 500 mg.

A person should be aware that caffeine at such dose may be life-threatening and it shouldn’t be mixed with alcohol.

A gram scale should be used to measure the dose to avoid overdosing.  


Side effects

Side effects of caffeine anhydrous include the following:

  • High blood pressure;
  • Increased heart rate (tachycardia) and palpitations;
  • Headache;
  • Dizziness;
  • Blurred vision;
  • Nausea;
  • Vomiting;
  • Diarrhea;
  • Dryness of the mouth;
  • Irritability;
  • Restlessness;
  • Insomnia;
  • Sweat/hyperhidrosis;
  • Loss of appetite;
  • Seizures;
  • Stupor and disorientation;
  • Addiction;
  • Overdose and combination with alcohol may lead to a lethal outcome;



The dosage should be measured accurately. People with heart diseases are not recommended to use pure caffeine powder.

The FDA recommends to avoid anhydrous caffeine, as long as several deaths related to powder caffeine have been reported.

Caffeine tolerance test

Caffeine tolerance test


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