Arterial occlusive disease
- High blood pressure.
- High cholesterol.
- Family history of atherosclerosis.
- People who are obese.
- Advanced age.
- Sedentary lifestyle.
- Severe aching pain in their toes or feet at night.
- The most severe forms of lower extremity peripheral vascular disease manifest as ulcerations or sores of the toes and feet that fail to heal and gangrene.
- Arm pain.
- Pain at rest.
- Pain in the legs at night.
- Cold feet.
- Hair loss on the arms or legs.
- Red, blue, or pale skin on the affected limb.
- Sores on the arms or legs that would not heal.
- Duplex ultrasound.
- Magnetic resonance angiography.
- Computed tomography angiography.
- Inositol nicotinate.
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