Chronic interstitial nephritis

Chronic interstitial nephritis: Description, Causes and Risk Factors:Chronic interstitial nephritisChronic interstitial nephritis is a clinicopathologic syndrome, their primary process involving the renal interstitial and related structures, as time goes by, causing a series of characteristic dysfunction. If accompanied by interstitial inflammation, should call chronic interstitial nephritis. Pathological changes are usually only see atrophy, sclerosis or tumor infiltration.Causes and Risk Factors May include:Obstructive nephropathy renal papillary parts of more than half of the following urinary tract obstruction is a primary cause of it.Infectious Agents:Bacteria: Legionella, Brucella, Corynebacterium diphtheriae, Streptococcus, Staphylococcus, Yersinia, Salmonella, E. coli, Campylobacter.
  • Viruses: Epstein-Barr virus (EBV), Cytomegalovirus, Hanta virus, Human immunodeficiency virus, Herpes simplex, Polyomavirus, Hepatitis B virus.
  • Other Agents: Mycoplasma, Rickettsia, Leptospira, Mycobacterium tuberculosis, Schistosoma mekongi, Toxoplasma, Chlamydia.
Hereditary Diseases:Autosomal dominant polycystic kidney disease.
  • Medullary cystic disease-juvenile nephronophthisis.
Metabolic Disturbances:Hypercalcemia/nephrocalcinosis. Immune-Mediated Disorders:Renal allograft rejection.
  • Wegener granulomatosis.
  • Sj

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