Endocrine dyscrasia

Endocrine dyscrasia: description, causes and risk factors
Endocrine dyscrasia is an age-related dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis and is associated with dyotic signaling and the induction of neurodegenerative cascades within the brain.In winter, people have vigorous metabolism, so that a great quantity of water and neutrino in our body is easier to run away, accompanying the wastage of these nutritious elements, the phenomenon of endocrine dyscrasia would also occur frequently.endocrine dyscrasia MedigooIncretion is the controller for regulating the physiological function, it plays its role in our body by excreting hormone. But if some reason causes the abnormal secretion of hormone, too much or too little, and the disorder of metabolism, the endocrine dyscrasia would occur.The modern females would shoulder bigger pressure both from live and work, so they are more easily visited by exogenous evil like wind, cold, heat, moisture and hot, consequently, they are more easily suffer the endocrine dyscrasia.These endocrine changes, and particularly, the elevation of gonadotropins concentrations and the loss of sex steroid signaling, have been recently linked to the development of Alzheimer's disease (AD). Current evidence also indicates that in AD, the in?ammation (and thus, the expression of pro-inflammatory cytokines) is most likely an early step that initiates the disease rather than a late step that minimizes the disease.Researchers suggest that both the loss of sex steroids/inhibins and the elevation of GnRH (gonadotropin-releasing hormone) with age-related endocrine dyscrasia, would serve to elevate TNF (tumor necrosis factor) expression in the brain. According to the authors, better understanding of these widespread functional links between the gonadotropins, sex steroids, and TNF may provide further insights into the pathogenesis of, and therapy for, neurodegenerative diseases.

Other Risk Factors:

  • Acromegaly, an overproduction of growth hormone, and prolactinoma, an overproduction of prolactin hormone, resulting from damage to the pituitary gland.
  • Addison's disease and Cushing's syndrome, disorders relating to changes in levels of hormones produced by the adrenal glands.
  • Diabetes mellitus, which arises when the pancreas does not produce sufficient insulin or when the body cannot respond to the insulin that is present.
  • Environmental or nutritional factors, such as a lack of iodine in hypothyroidism, which can affect hormone production.
  • Genetic factors, which may play a role in endocrine disorders, especially with diabetes and other disorders, such as autoimmune thyroiditis, or Hashimoto's thyroiditis.
  • Hyperthyroidism (overactive thyroid), hypothyroidism (underactive thyroid), Graves' disease (a type of hyperthyroidism resulting in excessive thyroid hormone production), and Hashimoto's thyroiditis (autoimmune disease resulting in hypothyroidism), all resulting from problems with the thyroid gland.
  • Tumors, since the underlying cause of the endocrine disorder can be linked to a growth or tumor of the gland.

Endocrine Dyscrasia Symptoms:

The concrete symptom for endocrine dyscrasia includes the chloasma on the face, lump in breast, hyperlipidemia and so on. These diseases not only are harmful to females' beauty, but also would damage the females' psychological and physiological health. This also can produce a vast array of other symptoms, including extreme fatigue, loss of appetite, rapid weight loss or gain, or body pain.


  • Understand where diseases and disorders begin. For instance, your pancreas works with various hormones, which if are out of control, can produce tumors and other malformations. Your thyroid also produces hormones that run your entire body and can be a common location for cancer cells.
  • Pay attention to changing hormonal cycles. If you are a woman, carefully keep track of your menstrual cycles and their regularity. Many a times women may face drastic hormonal imbalances, resulting in abnormally long cycles or none at all. If you have extreme pain during your cycle, see your doctor.
  • Find out if your family has a history of diabetes. This is hands-down one of the most common endocrine disorders, affecting millions of people in the world. You should be tested for diabetes on a yearly basis and should look out for symptoms, including extreme thirst, weight loss or gain, dizziness, and fatigue.
  • Another common disorder occurs with this is adrenal gland disorder, which obstructs how much cortisol or sex hormones your body produces. This can be an especially dangerous disorder, as abnormal growths can grow as a result of this disease.


There is no known cure. The people suffering endocrine dyscrasia, they should start with the following aspects:
  • First, acquire the good lifestyle, and form the regular rule of life. The irregular lifestyle would cause the disorder of human body's biological clock, keeping this bad lifestyle for too long, we would suffer such symptoms as deterioration of memory, appetite reduction, feeling tired all day, not easy to fall asleep at night, so that our body could not receive enough rest, naturally, the immunity would decrease, and our body are more easily attacked by diseases.
  • Second, insure enough sleep and nutrition, eat more fruit, vegetable, and foods with high-level protein and fiber.
  • Third, avoid of overstrain and keep a pleasure mood.
  • Fourth, eat the fast food less and get far away from the toxins. Excessive intake of saturated fats can stimulate excessive secretion of estrogen, and the steroid in fat can be converted into estrogen in the body, prompting the formation of breast cancer cells. If you intake too much artificial hormones, you will accumulate too many toxins in the body and cause endocrine dyscrasia. Moreover, use fewer plastic products containing food, because it is easy to cause the overflow of toxic substances. The soybeans and soy products can be effective in preventing endocrine disorders. Soybeans and soy products contain large amounts of plant estrogen, which plays an important part in the prevention of breast cancer, particularly the soybeans, can change the secretion of hormones. Clinical studies have shown that soybeans and soy products can balance the estrogen in the body, when the estrogen is too low, the soybeans or soy products will make it increase, while if it is woo high, they can also let the estrogen decrease.
In short, the prevention of endocrine dyscrasia needs your continuous efforts, in addition to the exercises and diet, keeping a happy mood is also very important.NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.


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