Frambesia tropica

Frambesia tropica: Description, Causes and Risk Factors:An infectious tropical disease characterized by the development of crusted granulomatous ulcers on the extremities; may involve bone, but, unlike syphilis, does not produce central nervous system or cardiovascular pathology.Frambesia tropics and syphilis have certain similarities and still other dissimilarities. Historically, the diseases have been associated more closely than is ordinarily known. The claim has been made that Frambesia and syphilis may be recognized from Biblical descriptions. This is far-fetched. More likely, the two diseases were uncovered after the discovery of America. Oviedo described the -disease as "bubas", a name by which Frambesia is still known in the West Indies. It is especially interesting to note that one of the earliest works accredited as proving that syphilis in Europe originated in America is entitledWidespread campaigns in the 1950s and 1960s to wipe out yaws through penicillin treatment have dramatically decreased the number of cases worldwide.Symptoms:About 2 - 4 weeks after infection, the person develops a sore called a "mother yaw" where Frambesia tropicaentered the skin. The sore is a growth that may be tan or reddish and looks like a raspberry. It is usually painless but does cause itching.These sores may last for months. More sores may appear shortly before or after the mother yaw heals as the person scratches or spreads the bacteria from the mother yaw to uninfected skin. Eventually the skin sores heal.Other symptoms include:Bone pain.
  • Scarring of the skin.
  • Swelling of the bones and fingers.
  • In the advanced stage, sores on the skin and bones can lead to severe disfigurement and disability. This occurs in up to 1 in 5 people who do not get antibiotic treatment.
Diagnosis:Diagnosis may include a microscopic examination. Asample from a skin sore is examined under a special type of microscope (darkfield examination).There is no blood test for frambesia tropica. However, the blood test for syphilis is usually positive in people with Frambesia tropica because the bacteria that cause these two conditions are closely related.Treatment:Treatment involves a single dose of one type of penicillin, or 3 weekly doses for later stage disease. It is rare for the disease to return. Anyone who lives in the same house with someone who is infected should be examined for frambesia tropica and treated if they are infected.NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.


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