Hamartoma

Hamartoma: Description, Causes and Risk Factors:HamartomaA hamartoma is defined as a focal growth that resembles a neoplasm but results from faulty development in an organ. They can occur anywhere in the body. They have been described in many organs but especially the chest, breast, skin and brain. They are also reported in the eye, colon and liver. Hamartomas are more frequent in men than women.Hamartomas result from an abnormal formation of normal tissue, although the underlying reasons for the abnormality are not fully understood. They grow along with, and at the same rate as, the organ from whose tissue they are made, and, unlike cancerous tumors, only rarely invade or compress surrounding structures significantly.Types may include: Fibrous hamartoma of infancy and pulmonary hamartoma.Hemangioma is a form of hamartoma where the growth is made up of vascular tissue.
  • A pulmonary hamartoma or benign lung growth actually accounts for nearly 75% of all benign tumors that are found in the lungs. The growths are made up of tissues that are found in the lungs, such as fat, fibrous tissue, and epithelial tissue.
  • Hypothalamic hamartoma are found near the hypothalamus, near the base of the brain.
There are many different kinds of hamartomas; however, it is important to distinguish them from a related form of benign tumor called a choristoma. Choristomas also contain normal tissue, but they are typically found in locations that are abnormal. Hamartomas differ based on their location. For example, hemangiomas, pulmonary hamartomas, and hypothalamic hamartomas are among the most researched conditions - each located in a different area of the body.Symptoms:Symptoms depend upon the site of the lesion and they may present at any time from birth to middle age but usually early in life.There may be a disfigurement of the skin.Diagnosis:If an intracranial hamartoma is suspected a CT or MRI scan is required.CT or MRI of the chest or mammography may produce enough confidence in the diagnosis.Biopsy: A simple surgical procedure by which a physician removes a small sample of affected body tissue so that it can be studied on a cellular level to identify the cause of the symptoms.Treatment:Management depends upon a firm diagnosis followed by appropriate action. Most isolated lesions can be ignored. If it is part of a syndrome like tuberous sclerosis or Cowden's syndrome the management is as for that disease. For severe cases surgery may be needed.Disclaimer: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.

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