Histoplasma capsulatum infection

Histoplasma capsulatum infection: Description, Causes and Risk Factors:Histoplasma capsulatum infectionHistoplasma capsulatum infection is an infection in the lungs caused by inhaling the spores of a fungus, Histoplasma capsulatum. It is common in most of the central and eastern United States. The fungus grows in soil, as well as bird and bat droppings. It is spread by breathing in the spores of disturbed soil.Many Histoplasma capsulatum infections do not produce symptoms. The illness occurs in two forms. The acute form is much like a mild case of influenza and is rarely serious.The chronic form, which is much less common, may resemble tuberculosis. In rare cases, the disease will spread throughout the body. This is most likely to happen in the very young, the very elderly and people with impaired immune systems, including people with cancer and AIDS. If histoplasmosis has spread, it can be life-threatening if it is not treated. People who have a chronic lung disease, such as COPD, are at higher risk of a more severe infection.Risk Factors:Chimney cleaner.
  • Construction worker.
  • Demolition worker.
  • Farmer.
  • Gardener.
  • Heating and air-conditioning system installer or service person.
  • Roofer.
  • Spelunker (cave explorer).
  • Bridge inspector or painter.
  • Restorer of historic or abandoned buildings.
  • Pest control worker.
  • Microbiology laboratory worker.
Symptoms:A general ill feeling.
  • Fever.
  • Chest pains.
  • Cough that doesn't bring up mucus.
  • Excessive sweating.
  • Coughing up blood.
  • Shortness of breath.
  • Headache.
  • Neck stiffness.
  • Mouth sores.
  • Skin lesions.
Diagnosis:How the disease is diagnosed depends on which parts of the body are affected. A chest x-ray may be able to detect Histoplasma capsulatum infection. In some cases, the doctor may take samples of blood, urine, sputum, or take tissue from your lymph nodes, lung or bone marrow to look for the fungus.Liver enzymes and kidney function tests and other blood tests including inflammatory markers (PCT, IL-6, CRP, SAA), tumor markers (AFP, CEA, CA19-9, CA-125), autoantibodies, antibodies related to infectious diseases including hepatitis B & C virus, and human immunodeficiency virus (HIV) tests during the hospital stay.Treatment:Currently, treatment with AmphocinSM is only recommended for severe pulmonary or disseminated disease and then only as an initial therapy, with a shift to an azole agent when the patient's symptoms improve. Itraconazole (antifungal agent) is the preferred choice for treatment of mild-to-moderate histoplasmosis. Voriconazole, for the treatment of relapse after initial therapy with itraconazole is another treatment option.NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.

0 Comments

Submit a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Cart Preview

The Uterus Interacts with the Brain and Affects the Memory, Study

The Uterus Interacts with the Brain and Affects the Memory, Study

New research from Arizona State University in Tempe, US, suggests that uterus may interact with the brain and influence the memory. For the study, a team of researchers used a rat model. The female rats were included into four groups, and the rats from three groups...

Risk of Heart Attack Peaks at 10pm on Christmas Eve Due to Stress

Risk of Heart Attack Peaks at 10pm on Christmas Eve Due to Stress

A new Swedish study finds that 10 pm on Christmas Eve is the peak time for the risk of having a heart attack, for the senior people and people with the existing issue in particular. For the study, a team of researchers analyzed data from 283,014 cases of heart attack...

[WpProQuiz 1]

Featured Products