Histoplasma capsulatum infection

Histoplasma capsulatum infection: Description, Causes and Risk Factors:Histoplasma capsulatum infectionHistoplasma capsulatum infection is an infection in the lungs caused by inhaling the spores of a fungus, Histoplasma capsulatum. It is common in most of the central and eastern United States. The fungus grows in soil, as well as bird and bat droppings. It is spread by breathing in the spores of disturbed soil.Many Histoplasma capsulatum infections do not produce symptoms. The illness occurs in two forms. The acute form is much like a mild case of influenza and is rarely serious.The chronic form, which is much less common, may resemble tuberculosis. In rare cases, the disease will spread throughout the body. This is most likely to happen in the very young, the very elderly and people with impaired immune systems, including people with cancer and AIDS. If histoplasmosis has spread, it can be life-threatening if it is not treated. People who have a chronic lung disease, such as COPD, are at higher risk of a more severe infection.Risk Factors:Chimney cleaner.
  • Construction worker.
  • Demolition worker.
  • Farmer.
  • Gardener.
  • Heating and air-conditioning system installer or service person.
  • Roofer.
  • Spelunker (cave explorer).
  • Bridge inspector or painter.
  • Restorer of historic or abandoned buildings.
  • Pest control worker.
  • Microbiology laboratory worker.
Symptoms:A general ill feeling.
  • Fever.
  • Chest pains.
  • Cough that doesn't bring up mucus.
  • Excessive sweating.
  • Coughing up blood.
  • Shortness of breath.
  • Headache.
  • Neck stiffness.
  • Mouth sores.
  • Skin lesions.
Diagnosis:How the disease is diagnosed depends on which parts of the body are affected. A chest x-ray may be able to detect Histoplasma capsulatum infection. In some cases, the doctor may take samples of blood, urine, sputum, or take tissue from your lymph nodes, lung or bone marrow to look for the fungus.Liver enzymes and kidney function tests and other blood tests including inflammatory markers (PCT, IL-6, CRP, SAA), tumor markers (AFP, CEA, CA19-9, CA-125), autoantibodies, antibodies related to infectious diseases including hepatitis B & C virus, and human immunodeficiency virus (HIV) tests during the hospital stay.Treatment:Currently, treatment with AmphocinSM is only recommended for severe pulmonary or disseminated disease and then only as an initial therapy, with a shift to an azole agent when the patient's symptoms improve. Itraconazole (antifungal agent) is the preferred choice for treatment of mild-to-moderate histoplasmosis. Voriconazole, for the treatment of relapse after initial therapy with itraconazole is another treatment option.NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.


Submit a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Cart Preview

Just 10 Minutes of Light Physical Activity May Boost Memory

Just 10 Minutes of Light Physical Activity May Boost Memory

A new study, performed by an international team of researchers from the University of California, Irvine, USA, and the University of Tsukuba, Japan, suggests that only 10 minutes of light physical activity may boost your memory. To check their hypothesis, the...

Ketogenic Diet May Be Actually Harmful to Your Health

Ketogenic Diet May Be Actually Harmful to Your Health

Recent research, performed by Sara Seidelman, a cardiologist and nutrition researcher from Brigham and Women’s Hospital in Boston, USA, finds that diets which ban entire food groups from the eating plan, for example, ketogenic diet, may actually harm your health. The...

[WpProQuiz 1]

Featured Products

The 5 Best Accessories for Sports Fans

It is very entertaining to be a sport fan. There is a big variety of sport games that are extremely interesting to follow. Moreover, it is always fun to anticipate the score and watch the enthusiasm live. One of the benefits of being sports fan is using different...

read more

Exercise May Serve as an Antidepressant

A new study of nearly 18,000 participants found that those with high fitness at middle age were significantly less likely to die from heart disease in later life, even if they were diagnosed with depression. Doctor's Tips: How to Stay Fit While Treating Depression Dr....

read more

Fitness: Warm Ups Can Chill Out the Perfomance

The warm ups are supposed to increase body temperature and blood flow so the muscles and surrounding joints become more responsive and prepared for physical activity. Although there’s a neurological element to warm-ups, most research focuses on the physiological...

read more