Description, Causes and Risk Factors:
Alternative Names: Granuloma Fungoides.
A chronic progressive lymphoma arising in the skin that initially simulates eczema or other inflammatory dermatoses. In advanced cases, ulcerated tumors and infiltration of lymph nodes may occur. The disease often infects the skin, but it can spread to various other parts of the body including the blood and internal organs with varying degrees of severity. A large majority of the patients with mycosis fungoides will generally have to live with the disease for the rest of their lives as there are no real known cures. One can only attempt to treat the symptoms and to alleviate some of the complications that are associated with it.
The causes of mycosis fungoides is yet unknown. Genetic predisposition may play a role in some cases, and familial occurrence has been reported in a few instances. Association with long-term exposure to various allergens has also been advocated, as well as exposure to environmental agents and association with chronic skin disorders and viral infections. In some countries, mycosis fungoides-like disorders are clearly associated with viral infections (i.e., HTLV-I-associated adult T-cell lymphoma/leukaemia), but search for viral particles in patients with mycosis fungoides has been unsuccessful.
This disease is more common in males than in females and is seen in people over 20 years of age. The most common group of people affected by mycosis fungoides are those in their mid 40s and 50s and those who suffer from tumors, erythroderma or leukemia. These conditions are known to be most often paired with mycosis fungoides.
Mycosis fungoides is a rare disease. According to a survey, incidence was reported to be 0.36/105 person-years from 1973 to 1992 in the United States.
Other symptoms include:
Red scaly rash in skin.
Skin conditions include:
The diagnosis of early mycosis fungoides often needs integration of clinical, histological and molecular features since it can be confused with benign eczematous skin disease.
Some of investigation needed to confirm diagnosis include:
Uric acid: May be raised in aggressive disease.
Consider HIV testing (but the vast majority of patients are HIV-negative).
CT scan of the abdomen and pelvis: In patients with advanced disease (stage IIB to stage IVB) or in patients with clinically suspected visceral disease.
Skin biopsy: For a definitive diagnosis, skin biopsy shows mycosis or "S
Liver function tests: lactate dehydrogenase (LDH) is a marker of bulky or biologically aggressive disease. Abnormal transaminase values may indicate hepatic involvement.
A new study from the US discovers that flavonoids, natural compounds found in fruits and vegetables, may help preserve the lung function, which tends to decline with age. For the study, a team of researchers looked at data from 463 adults from Norway and England whose...
According to a recent study, published in The Journal of Physiology, exercising four to five times per week may help stop the main arteries to the heart from stiffening up. The researchers from the US have found that those who exercise four to five times per week had...
Quiz about this article
0 of 2 questions completed
Please answer on few questions to make our service more useful
You have already completed the quiz before. Hence you can not start it again.
Quiz is loading...
You must sign in or sign up to start the quiz.
You have to finish following quiz, to start this quiz:
0 of 2 questions answered correctly
Time has elapsed
You have reached 0 of 0 points, (0)
Question 1 of 2
Was this article useful for you?Correct
Thanks for your feedback!Incorrect
Thanks for your feedback!
Question 2 of 2
What else information about this disease you want to know ?Correct
Thanks for feedback!Incorrect
Thanks for feedback!
Good weather is the best reason to do outdoor sports, which will help not only lose weight, but also will strengthen health. Bicycle The sun dries out the local paths, so you can safely sit on your favorite bike and confidently twist the pedals, where the eyes look....read more
First aid for injuries consists of simple rules that need to be clearly implemented. If this is a closed injury, you need to immobilize the injured limb, otherwise the person may lose consciousness from a painful shock. If you need to get to the emergency room...read more
Many people spontaneously decide starting to do sport, while others weigh all the pros and cons for a log time. But almost all of them make the same mistakes, listening to the advice of non experts. There are 10 anti-tips for those who want to do plan to do some sport...read more