Pachydermia laryngis

Pachydermia laryngis: Description, Causes and Risk Factors Pachydermia laryngis is a rare disorder characterized by thickening of the laryngeal epithelium. It appears as excess, uneven and rough tissue in the space between the arytenoid cartilages. The membranous vocal folds may also become thickened. Of late pachydermia laryngis has occupied a prominent place in the writings of laryngologist, more especially in those in of our German. The disease usually attack the posterior extremities of the vocal cords.Pachydermia laryngis Medigoo Whilst the cause of the disease is unknown, smoking and irritation resulting from GERD (gastroesophageal reflux disease) may be contributing factors. Some of the triggering factors may include: Tabacco.
  • Excessive use of alcholol.
  • Vocal abuse.
  • Chronic postnasal discharge with laryngeal irritation.
  • Syphillis.
  • Endocrine dyscrasia.
  • Vitamin A and B deficiency.
  • Virus infection.
  • Mycosis.
The resechers says the the disease may be due to two causes. Firstly, that in consquences of the superfical layers of the soil becoming dry, pathogen organism, which would under other circumstances adhere to the earth are sucked up into the houses in the form of minute dust by current of ground air, which ever forms a portion of the atmosphere of ordinary houses. Secondly, that large quantities of sewage, which in time of heavy rainfall would be swept out of place, remain in miles and lies of large sewers, and there forment and decompose. Thus the epidemic wave seems to be greatest when the first rainfalls, after a lengthened period of dry weather, being bust slight are sufficient to stimulate to activity the dry and comparatively inert organic matter, and it only passes away with the thorough dusting of the sewers such as we obtained after the heavier and longer-continued showers of the latter half of the July. Symptoms: Symptom may include: Hoarse voice.
  • Cough.
  • Dyspnea.
  • Stridor.

Pachydermia laryngis Diagnosis:

The objective mirror examination is characteristic. The physician may find discrete or confluent, flat or papillary, grey-white, irregular patches covering the laryngeal mucosa. The patches may occasionally involve one side only, but more often they are irregularly bilateral in distribution. One may observe strict demarcation between normal mucosa and the borders of involved tissue. There is always an inflammatory cell infiltration of the subepithelial tissue. Treatment: Treatment Options: Both medical and surgical techniques are usually employed. In general, medical management is based on variety of therapeutic agents. Some of the more common ones are sulfonamide drugs and penicillin. The antibiotics administered by aerosol, lozenges, spray and by oral parenteral methods. Apart from this vitamin supplementation may also be helpful. From the surgical viewpoint, stripping of the involved laryngeal mucous membrane is considered as treatment of choice. The surgery will performed under general anesthesia. Technically, this procedure may be carried out with the aid of the Robert retention laryngoscope, Lynch suspension laryngoscope, or laryngeal forceps. NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.


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