Tinea profunda


Tinea profunda

Description, Causes and Risk Factors:

Alternative Name: Majocchi granulomas.

ICD-10: B35.8.

Tinea profunda is also known as nodular granulomatous perifolliculitis, is an uncommon fungal folliculitis. It has been described as, “certain superficial fungus diseases which sometimes exhibit fungal elements invading the epidermis, pilosebaceous follicles and dermis to mimic deep cutaneous mycotic disorders.”

Tinea profunda is observed among immunocompetent and immunocompromised patients and is caused by dermatophytes, particularly Trichophyton rubrum, which may be responsible for 50% of cases. Other causes may include T. mentagrophytes and Epidermophyton floccosum. Experts do not know whether these granulomas appear in response to the organism itself, or after the release of follicular contents. It commonly occurs in young women that shave their legs frequently.

The mechanism by which it occurs is yet unknown although reports suggest it may occur after localized trauma that alters the hair follicle and enables the entrance of the microorganism.

Tinea profunda has two clinical presentations, among immunocompetent patients it displays follicular papules and among immunocompromised patients a subcutaneous nodular type is observed.

Symptoms:

Symptoms include patches on any hairy area, such as the scalp, face, forearms, hands, and legs. Tinea profunda may be worsened by shaving legs in an upward direction, which causes the hair follicles to be inoculated with athlete's foot fungus. The lesions may first appear as single or multiple oval patches that evolve into pustules and nodules with or without background redness and scaling.

If the condition is associated with the use of topical steroids, they may be affected by the complications of topical steroid therapy, including atrophied skin and spidery veins, rosacea, or patches of loss of color on the skin that looks like leprosy.

Diagnosis:

Based on the clinical morphology, the differential diagnosis largely includes other conditions that follow a follicular pattern, such as variations of folliculitis, acne, pseudofolliculitis barbae, eosinophilic pustular folliculitis and acne keloidalis.

Fungal elements can be viewed on H&E (hematoxylin and eosin stain), but PAS (periodic acid-Schiff stain) and GMS (Gomori methenamine silver stain can also be used.Histology alone cannot identify the causative organism, but fungal culture can confirm the suspected fungus.

Treatment:

Tinea profunda usually responds to topical antifungal or drying powders, such as those that contain miconazole, clotrimazole, or similar ingredients. Severe or chronic infection may require further treatment by a doctor. Stronger, prescription topical antifungal medications, such as ketoconazole or sulconazole, may be needed. In some cases, topical corticosteroids may be added to the topical antifungals. Antibiotics may be needed to treat secondary bacterial infections.

NOTE: The above information is educational purpose. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition.

DISCLAIMER: This information should not substitute for seeking responsible, professional medical care.

0 Comments

Submit a Comment

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Cart Preview

Regular Walking May Reduce Stroke Severity

Regular Walking May Reduce Stroke Severity

A new study, conducted by the scientists from the University of Gothenburg in Sweden, finds that light and moderate physical activity, for example walking and swimming, may help reduce the stroke severity. The study included approximately data from 1,000 individuals...

Regular Use of Probiotics May Cut the Need for Antibiotics

Regular Use of Probiotics May Cut the Need for Antibiotics

According to the latest study, published in the European Journal of Public Health, regular use of probiotics may cut the necessity for antibiotics and help decrease the rise of antibiotic resistance. Having performed the analysis of the data, collected from recent...

[WpProQuiz 1]

Featured Products

The 5 Best Accessories for Sports Fans

It is very entertaining to be a sport fan. There is a big variety of sport games that are extremely interesting to follow. Moreover, it is always fun to anticipate the score and watch the enthusiasm live. One of the benefits of being sports fan is using different...

read more

Exercise May Serve as an Antidepressant

A new study of nearly 18,000 participants found that those with high fitness at middle age were significantly less likely to die from heart disease in later life, even if they were diagnosed with depression. Doctor's Tips: How to Stay Fit While Treating Depression Dr....

read more

Fitness: Warm Ups Can Chill Out the Perfomance

The warm ups are supposed to increase body temperature and blood flow so the muscles and surrounding joints become more responsive and prepared for physical activity. Although there’s a neurological element to warm-ups, most research focuses on the physiological...

read more