A team of scientists from the National Center for Nanoscience and Technology in Beijing, China, developed a DNA platform able to carry chemotherapy drugs into specific cancer cells as well as silence the cells’ drug-resistant genes.
The team has successfully tested the ability of the DNA platform to selectively deliver RNA transcription templates and the chemotherapy drug doxorubicin in cell cultures and then in mice with multidrug-resistant tumors.
The received results demonstrated that the DNA tool was efficient both at the selective delivery and release of the two items which also led to a highly-selected tumor kill rate.
The authors conclude in their paper: “This tailored DNA nanoplatform, which combines RNAi therapy and chemotherapy, provides a new strategy for the treatment of multidrug-resistant tumors.”
New research from Florida State University suggests that eating cottage cheese before going to bed may boost metabolism and strengthen the muscle and immune system due to the high content of protein.
For the study, a team of researchers checked the effect of eating cottage cheese before bed on 10 women aged between 20 and 30. Each woman ate 30g (1oz) of cottage cheese 30–60min before sleep.
Having analyzed the results of tests, the scientists concluded that women’s bodies were just as efficient after cottage cheese as when they were given a casein shake before bed.
The study author Professor Michael Ormsbee says: “Until now, we presumed whole foods would act similarly to the data on supplemental protein, but we had no real evidence. This is important because it adds to the body of literature that indicates whole foods work just as well as protein supplementation. And it gives people options for pre-sleep nutrition that go beyond powders and shaker bottles.”
A large-scale study by scientists from the Cleveland Clinic in Ohio finds that even large amounts of aerobic exercise still increase the lifespan, especially in older people.
For the study, a team of researchers led by Dr. Wael Jaber who is a cardiologist at the Cleveland Clinic has analyzed the data from 122,007 people who participated in exercise treadmill testing from January 1, 1991, to December 31, 2014. The scientists paid the special attention to the link between aerobic exercises and lifespan.
Having analyzed the received data, the researchers concluded that higher levels of aerobic fitness were associated directly with the lower risk of long-term mortality.
Dr. Wael Jaber explains: “Aerobic fitness is something that most patients can control. And we found in our study there is no limit to how much exercise is too much […] Everyone should be encouraged to achieve and maintain high fitness levels.”
New Japanese research finds that linalool, a fragrant compound in lavender, can help lessen anxiety by stimulating the nose to pass signals to the brain, not by being absorbed into the bloodstream through the lungs.
World Health Organization (WHO), as of 2015, estimates that 3.6 percent of the global population suffers from anxiety disorders. The number varies from country to country.
Study co-author Dr. Hideki Kashiwadani, of the Graduate School of Medical and Dental Sciences at Kagoshima University, says: “Our study also opens the possibility that relaxation seen in mice fed or injected with linalool could, in fact, be due to the smell of the compound emitted in their exhale breath.”
A new study from Austria finds evidence that microplastics, such as extremely small pieces of plastic beads, fibers, or fragments, accumulate in human feces.
A team of scientist from the Environment Agency Austria and the Medical University of Vienna has analyzed the samples of excrements of eight participants from Italy, Japan, Poland, the Netherlands, Russia, the United Kingdom, Finland, and Austria.
All participants reported what they ate or drank within the week prior to the sampling. They all drank from plastic bottles and ate plastic-wrapped foods. According to the study, the sea animals consume plastic, humans are likely to ingest it by eating tuna, shrimp, or lobster.
The scientists report that the microplastics may take part in transmittance of toxic chemicals and pathogens to the human body which can lead to the weakening of the immune response of the gut.