Body Clock May Have Crucial Influence on Immune System

A new study, conducted by the team of researchers from the Douglas Mental Health University Institute and the Université de Montréal, Canada, suggests that the body clock may have a great influence on the immune system. The study finds that the immune system responds differently throughout the day.Body Clock May Have Crucial Influence on Immune System

To come to this conclusion, the scientists working with two groups of mice one of which was genetically modified by switching off specific genes responsible for the regulation of circadian rhythms while the second group had these genes active.

With the help of a specific vaccine, the researchers found that in mice with a deficit of clock genes the response to the vaccine was diminished in the daytime.

Co-author Prof. Nathalie Labrecque says: “Our study shows that T cells are more prone to be activated at certain times of the day. Identifying the mechanisms through which the biological clock modulates the T cell response will help us better understand the processes that regulate optimal T cell responses.”

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