High Doses of Common Painkillers Linked to Higher Risk of Heart Attack
A recent study, published in The BMJ, suggests that people who commonly take high doses of common non-steroidal anti-inflammatory painkillers, or NSAIDs, such as ibuprofen and naproxen, could be at a higher risk of a heart attack.
An international team of researchers with Michele Bally of the University of Montreal Hospital Research Center as a leader of the study analyzed health care data of 446,763 people from Canada, Finland, and the United Kingdom, among whom 61,460 had a heart attack.
High doses were considered as following: > 200 mg for Celecoxib (Celebrex), > 100 mg for Diclofenac (Voltaren, Cambia, Solaraze), > 1200 mg for Ibuprofen (Advil), > 750 mg for Naproxen (Midol, Aleve, Naprelan).
Deepak Bhatt, M.D., executive director of an interventional cardiovascular program at Brigham and Women’s hospital, says: “The bottom line [of the study] is, don’t treat these drugs like candy just because they're sold over the counter said. Treat them like any medications. Only use them if you really need to, lowest dose possible, for least amount of time.”
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