COVID-19 Vaccine for Intranasal Administration Shows Promise

The scientists from Washington University School of Medicine in St. Louis, US, developed and tested an experimental COVID-19 vaccine for intranasal administration. They found that just one dose may protect against infection in mice susceptible to the coronavirus.COVID-19 Vaccine for Intranasal Administration Shows Promise

The researchers gave the vaccine to mice either intranasally or by injection to check its efficacy. The injection caused an immune response that prevented pneumonia, but it could not prevent the infection from spreading to the lungs. At the same time, the intranasal administration prevented infection in the upper and lower respiratory tracts (the nose and lungs).

Senior study author Prof. Michael Diamond says: “In these mouse models, the vaccine is highly protective. We’re looking forward to beginning the next round of studies and ultimately testing it in people to see if we can induce the type of protective immunity that we think not only will prevent infection but also curb pandemic transmission of this virus.”

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