Newly Discovered Key Components of HIV Can Lead to More Effective Drugs
Researchers from the Medical Research Council Laboratory of Molecular Biology in Cambridge and University College London, United Kingdom, discovered key components of HIV which can lead to new approaches for drugs for this infection.
A protein shell called capsid surrounds the virus. Now the scientists uncovered that the capsid contains iris-like pores that can open and close like an eye.
These pores open and close very quickly and that enables them to “suck in” the genetic building blocks called nucleotides that the virus needs to build the DNA to infect the cell, keeping out any unwanted molecules. This discovery helps to explain why HIV can successfully evade the immune system of the body.
Dr. Leo James from the Medical Research Council Laboratory of Molecular Biology says: “We used to think that the capsid came apart as soon as the virus entered a cell but now realize that the capsid protects the virus from the innate immune system. The channels we’ve discovered explain how the fuel for replication gets into the capsid to allow the viral genome to be made.”
More details here.
Raised sensitivity to bitter tastes might be an indicator of higher risk of cancer in women, according to a new research, conducted by scientists at the College of Agriculture Sciences of Pennsylvania State University in State College (US) in association with a team...
A new study from the Stevens School of Business in New Jersey, USA, finds that even coffee scent can sharpen the brain under certain conditions. In the study, 114 students were involved. The participants were divided into two group and both had to answer mathematical...
We all know that doing sports is very important, both for health and for a beautiful body. But at the moment when we decide to finally take the path, we are faced with the question: what kind of sport is right for me? So, let's start with the fact that a lot of people...read more
Pranayama is not just a complex of breathing exercises. It is a complex process, during which a person receives vital energy - prana from the air. Literally pranayama is translated as "stopping breathing". Hence the main goal of the whole breathing gymnastics is to be...read more
Experts often advise people as suitable trainings to climb stairs, rather than use the elevator. And here are 6 reasons why we should do this regularly. Classes on the treadmill or with the ellipsoid simulator in daily mode seem too boring. They can be replaced by a...read more