Gene Variant Increasing the Risk of Dying from COVID-19 Identified

Researchers from the University of Oxford found that the gene LZTFL1, which is involved in the regulation of lung cells in response to infection, has a variation that can double the risk of death from COVID-19 for people younger than 60 years.Gene Variant Increasing the Risk of Dying from COVID-19 Identified

This gene variation is present in 60% of people of South Asian ancestry, 15% of people of European ancestry, 2.4% of people with African ancestry, and 1.8% of people with East Asian ancestry.

However, the researchers note that no single gene can explain every aspect of someone’s risk from a disease like COVID-19, because many factors play a role.

One of the study leaders, James Davies, a professor of genomics at the University of Oxford, says: “It's one of the more prevalent genetic signals, so it's by far the most important genetic hit in COVID.”

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