Gut Microbiome Can Boost the Immune System to Fight Cancer

A recent international study, published in Nature Communications, finds that gut microbiome can boost the immune system’s ability to fight cancer.gut microbiome boosts immune system to fight cancer

During the study, a team of researchers identified 11 strains of gut bacteria which helped the immune system to slow down the growth of melanoma tumors in mice. The scientists highlighted a signaling pathway called unfolded protein response (UPR) as a major link between the gut bacteria and the fighting ability of the immune system.

Senior study author Ze'ev Ronai, a professor at Sanford Burnham Prebys, says: “These results [...] identify a collection of bacterial strains that could turn on antitumor immunity and biomarkers that could be used to stratify people with melanoma for treatment with select checkpoint inhibitors.”

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