High Caffeine Consumption May Triple the Risk of Glaucoma

An international multi-center study, led by the Icahn School of Medicine at Mount Sinai, finds that regular consumption of large amounts of caffeine, more than 480 mg per day, may lead to a higher risk of glaucoma more than three-fold for people with a genetic predisposition to higher eye pressure.High Caffeine Consumption May Triple the Risk of Glaucoma

For the study, a team of scientists analyzed records of more than 120,000 individuals from the UK Biobank, a large biomedical database. The age of the participants was between 39 and 73 years. They provided their health records and DNA samples. They also answered regular dietary questionnaires.

Co-author Anthony Khawaja, MD, Ph.D., Associate Professor of Ophthalmology University College London (UCL) Institute of Ophthalmology and ophthalmic surgeon at Moorfields Eye Hospital, notes: “This study suggested that those with the highest genetic risk for glaucoma may benefit from moderating their caffeine intake. It should be noted that the link between caffeine and glaucoma risk was only seen with a large amount of caffeine and in those with the highest genetic risk.”

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