Hydroxychloroquine Has No Benefit over Placebo in Preventing COVID-19

The first randomized clinical trial, performed by the researchers from the University of Minnesota Medical School, shows that hydroxychloroquine is not able to prevent the development of COVID-19.Hydroxychlorine Has No Benefit over Placebo in Preventing COVID-19

The randomized placebo-controlled trial aimed to test if hydroxychloroquine could prevent COVID-19 infection in healthy persons after exposure to an individual diagnosed with COVID-19.

To study the effect of the said drug, the scientists enlisted 821 non-hospitalized adults from the US and Canada who were exposed to the novel coronavirus from someone living in their household or as a healthcare worker.

The results of the study showed that approximately 12% of people who received hydroxychloroquine developed COVID-19 versus approximately 14% of those who received the vitamin placebo (folate).

This was not a statistical difference, and even if there was a statistical difference, this would equate to treating 42 persons with hydroxychloroquine in order to prevent one infection. No further benefit to prevent infection among those who also took zinc or vitamin C was found.

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