Identified Clear Differences in the Brain Cells of People with Depression

New research from Douglas Mental Health University Institute and McGill University in Canada found a significant drop in the number of specific kinds of supportive nerve cells in individuals with depression who died because of suicide compared to people without the condition at the moment of death.Identified Clear Differences in the Brain Cells of People with Depression

For the study, a team of researchers analyzed brain tissue taken from 10 men diagnosed with depression who committed suicide. The taken samples were compared with 10 samples of tissue taken by post-mortem from different brain regions in men who died suddenly and didn’t have any mental-health diagnosis.

Neuroscientist Liam O'Leary, who completed this study, explains: “We analyzed the astrocytes in the brain by staining specific proteins found in their structure - vimentin and GFAP. Vimentin staining has not been used before in this context, but it provides a clear, complete, and unprecedented view of the entire microscopic structure of these cells.”

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