A Study Identified New Genetic Locations for Type 2 Diabetes
A team of scientists from University College London and Imperial College London, UK, discovered genetic locations that may help to understand why some people have higher chances to develop type 2 diabetes.
For their study, the researchers used a UCL-developed method of genetic mapping. Using this method, they examined samples of European and African people, what counts for 5,800 cases of the condition and 9,700 cases of healthy controls. The researchers found that the three locations coincided with chromosomal regions regulating gene expression, contain epigenetic markers. Present genetic mutations are suggested to cause type 2 diabetes.
Dr. Toby Andrew, a lead researcher, says: “Before we can conduct the functional studies required in order to better understand the molecular basis of this disease, we first need to identify as many plausible candidate loci as possible. Genetic maps are key to this task, by integrating the cross-platform genomic data in a biologically meaningful way.”
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