People with Higher Genetic Risk of Colon Cancer Benefit More from Lifestyle Changes

A new study, completed by researchers from Vanderbilt University Medical Center, suggests that people with a higher genetic risk of developing colorectal cancer could more successfully prevent the disease by applying lifestyle changes compared to those with lower genetic risk.People with Higher Genetic Risk of Colon Cancer Benefit More from Lifestyle Changes

For the study, a team of researchers analyzed data from participants in the UK Biobank. Having performed the analysis, the scientists concluded that leading a healthy lifestyle was associated with an approximately 40% reduction in colorectal cancer risk in people with a higher polygenetic risk score. However, the percentage was significantly lower, about 25%, in people at low genetic risk for this cancer.

Wei Zheng, MD, PhD, MPH, Anne Potter Wilson Professor of Medicine and associate director for Population Sciences Research at Vanderbilt-Ingram Cancer Center (VICC), believe that results from this study could be useful to design personalized prevention strategies for colorectal cancer prevention.

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