Red Wine Compound May Become Depression Treatment in Future
A new study in mice, conducted by the researchers from Xuzhou Medical University in China, suggests that resveratrol, a red wine compound, can be used for the treatment of depression and anxiety in the future.
In this study, the scientists used animal models and cultured mouse neurons (similar to those in the human hippocampus) to help explain the effect of the compound on rodent behaviors.
Resveratrol, which appears to reduce anxiety and depression in mice, seems to work by inhibiting PDE4D (a member of the PDE4 family that believed to be particularly important in cognition and depression) and activating cAMP (cyclic adenosine monophosphate) signaling.
Co-lead author Dr. Ying Xu, Ph.D. says: “Resveratrol may be an effective alternative to drugs for treating patients suffering from depression and anxiety disorders.”
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