Scientists Developed an Innovative Method to Treat Kidney Cancer

Researchers from the University of Surrey and Sechenov First Moscow State Medical University in Russia developed an innovative technique that forces cancer cells in the kidneys to self-destruct. This novel approach may revolutionize the treatment of the disease.Scientists Developed an Innovative Method to Treat Kidney Cancer

The developed approach focuses on cathepsin S, a member of the lysosomal cathepsin proteins that are associated with cancer progression, and p21 BAX, a protein that can stimulate cell destruction. The scientists discovered that these proteins can be deployed simultaneously to fight cancer cells in a two-pronged attack. Firstly, they stop the mechanism that makes certain treatments of the disease ineffective, and after this effectively encouraging cancerous cells to self-destruct.

Professor Paul Townsend, Principal Investigator, Pro-Vice-Chancellor, and Executive Dean of the Faculty of Health and Medical Sciences at the University of Surrey, comments: "Kidney cancer is a very difficult type of cancer to cure; there is an increased need to think innovative to develop new techniques. We have now discovered that proteins already in the body can be manipulated to encourage cancerous cells to die. This is an extraordinary breakthrough and insight, and can be used to potentially inform the treatment of other types of aggressive cancers, such as cancers of the breast and prostate.”

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