Scientists Moved One Step Closer to HIV Cure

A team of researchers from the universities of North Carolina and Emory in Atlanta moved one step closer to cure HIV forcing the AIDS-causing virus to reactivate meaning this virus becomes vulnerable to the immune system and medication.Scientists Moved One Step Closer to HIV Cure

This is a significant achievement as currently this virus hides at undetectable levels in immune cells and cannot be killed.

To shock and kill the virus hiding in immune cells, the team used a drug AZD5582 which forced open cellular pathways in the immune system. At the present moment, the drug was tested only on animals.

Co-senior author on both papers Ann Chahroudi, an associate professor of pediatrics and director of the Center for Childhood Infections & Vaccines at Emory, says: “AZD5582 was remarkable in its ability to reactivate latent SIV from resting CD4+ T cells, and to induce continued virus production in the blood when monkeys were still receiving daily antiretroviral therapy.”

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