Scientists Successfully Transplanted Tiny Lab-Grown Livers

Scientists have successfully transplanted functional miniature livers into rats. The organs were grown in the lab from reprogrammed human skin cells donated by the volunteers.Scientists Successfully Transplanted Tiny Lab-Grown Livers

Researchers transplanted organs into five rats, and the tiny livers appeared to be functional. After four days, the scientists performed tests that showed bioengineered livers secreted bile acids and urea. Also, human liver proteins in the blood of animals were another sign that the organs were working. However, the transplants didn’t function perfectly.

Pathologist Alejandro Soto-Gutiérrez from the University of Pittsburgh, one of the authors of the study, explains: “The long-term goal is to create organs that can replace organ donation, but in the near future, I see this as a bridge to transplant. For instance, in acute liver failure, you might just need a hepatic boost for a while instead of a whole new liver.”

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