Study from Japan: Healthy Microbiome Connected to Good Sleep

Recent research, conducted by researchers from the University of Tsukuba in Japan suggests that the gut microbiome can also influence normal sleep patterns by helping create important chemical messengers in the brain, such as serotonin and dopamine.Healthy Microbiome Connected to Good Sleep

For the study, the scientists divided 25 genetically identical 8-week old male mice into two groups and gave the first group access to water with 4 commonly used broad-spectrum antibiotics to deplete the mice's gut microbiota. The second group received water without antibiotics. After 4 weeks, the researchers found that the mice that drank the antibiotic water had much fewer intestinal metabolites than the control mice.

The lead author of the study Prof. Masashi Yanagisawa says: “We found that microbe depletion eliminated serotonin in the gut, and we know that serotonin levels in the brain can affect sleep-wake cycles. Thus, changing which microbes are in the gut by altering diet has the potential to help those who have trouble sleeping.”


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