Unhealthy Gut Microbiome Boosts the Spread of Breast Cancer
According to the new study from the University of Virginia, US, an unhealthy and inflamed gut microbiome may be the cause of breast cancer to become more aggressive and develop more quickly spreading to other parts of the body.
In the course of the study, the researcher Melanie Rutkowski, PhD, from the University of Virginia Cancer Center with the help of mouse model found that disrupting the microbiome lead to hormone receptor-positive breast cancer to become more aggressive.
The researcher comments: “When we disrupted the microbiome's equilibrium in mice by chronically treating them antibiotics, it resulted in inflammation systemically and within the mammary tissue. In this inflamed environment, tumor cells were much more able to disseminate from the tissue into the blood and to the lungs, which is a major site for hormone receptor-positive breast cancer to metastasize.”
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