Vitamin A May Help Treat Early Vision Loss in People with Diabetes

Recent research, published in The American Journal of Pathology, using a mouse model has found that treatment with vitamin A may significantly improve eyesight in those suffering from type 2 diabetes.Vitamin A May Help Treat Early Vision Loss in People with Diabetes

Researchers checked the effectiveness of the chromophore 9-cis-retinal in the treatment of vision loss in mice with diabetes. They used 9-cis-retinal instead of 11-cis-retinal produced by the body because the latter is highly unstable and not commercially available but they are closely related.

In the study, the mice with diabetes were divided into two groups, one of which received an injection of a single dose of 9-cis-retinal, while another group received a placebo. The analysis of the results showed that the mice that received treatment with 9-cis-retinal had significantly improved vision across all measures.

Lead researcher Dr. Gennadiy Moiseyev, from the University of Oklahoma Health Sciences Center in Oklahoma City, says: “This study suggests that the delivery of visual chromophore to the diabetic eye may represent a potential therapeutic strategy for the early stages of diabetic retinopathy to prevent vision loss in [people] with diabetes.”

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