A new study, conducted by a team of researchers from Salk Institute, US, shows how calorie restriction can protect against aging at a cellular level.
During the study, the team compared rats who ate 30% fewer calories with rats that had a normal diet. The rodents were followed from the age of 18 months and until they were 27 months (roughly equivalent to human age, from 50 through 70).
The scientists analyzed 168,703 cells from 40 cell types from fat tissues, liver, kidney, aorta, skin, bone marrow, brain and muscle in 56 rats at the start and the conclusion of the diet.
The analysis showed that many changes that occurred to rat on a normal diet when they grew older did not happen to those that were on a diet. In general, 57% of age-related changes in cell composition scientists noticed in the tissues of rats with a normal diet were not present in the rats with calorie restriction.
A new study, executed by researchers at Northwestern University in Illinois, US, finds that giving birth shortens a woman’s life by up to two years. That means the more children a woman has, the shorter her lifespan may be.
For the study, the researchers examined 3,200 women aged from 20 to 22 years in the Philippines. They found that every birth has a damaging effect at the cellular level, having looked at two markers of cellular aging —telomere length and epigenetic age. These two factors may predict mortality.
Lead author Calen Ryan says: “Both [markers] appeared ‘older’ in women who had more pregnancies in their reproductive histories. Even after accounting for other factors that affect cellular aging, the number of pregnancies still came out on top.”
Two new independent studies conducted in mice suggest that ketogenic diet, also known as “keto diet”, may improve the memory of old subjects and prolong lifespan.
One study was led by Drs. Eric Verdin and John Newman from the Buck Institute for Research on Aging in Novato, USA. Another study was led by Dr. John Ramsey from the University of California, Davis School of Veterinary Medicine.
Both studies checked the effects of four diet types such as ketogenic, low carbohydrate, high fat, and control diet in mice. A team of scientists from the Buck Institute found that a keto diet prevent obesity, reduced mid-life mortality, and prevented memory loss in mice.
Dr. John Ramsey says: “We expected some differences [in mice fed the keto diet], but I was impressed by the magnitude we observed – a 13% increase in median life span for the mice on a high-fat versus high-carb diet. In humans, that would be 7 to 10 years. But equally important, those mice retained quality of health in later life.”
A recent research from the UK, published in the medical journal BMJ, suggests that even moderate drinking may cause changes in aging brains and lead to eventual memory loss.
Within the scope of the study, the scientists considered 8 to 12 small glasses of wine, bottles of beer or shots of liquor weekly as a moderate drinking. For their study, a team of researchers examined three decades of records from 527 British civil servants who were a part of a prolonged health study.
Lead researcher Anya Topiwala of the University of Oxford says: “I wouldn’t recommend light to moderate drinking as a strategy to avoid cognitive decline. It’s not clear how much drinking might be safe from a brain health standpoint.”
Previously, it was thought that senior people just need less sleep than youth, but a new research has discovered that adults begin losing their ability to lapse into a deep and restorative sleep from about their middle thirties.
For the study, the researchers analyzed the scientific literature published in the medical journal Neuron. The scientists also found that we also start showing signs of aging.
One of the authors of the study Professor Matthew Walker says that it is the lack of sleep also linked to a number of deadly diseases, especially those affecting the brain. He explains: “Sleep changes with aging, but it doesn’t just change with aging; it can also start to explain aging itself.”
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