A team of researchers from the universities of North Carolina and Emory in Atlanta moved one step closer to cure HIV forcing the AIDS-causing virus to reactivate meaning this virus becomes vulnerable to the immune system and medication.
This is a significant achievement as currently this virus hides at undetectable levels in immune cells and cannot be killed.
To shock and kill the virus hiding in immune cells, the team used a drug AZD5582 which forced open cellular pathways in the immune system. At the present moment, the drug was tested only on animals.
Co-senior author on both papers Ann Chahroudi, an associate professor of pediatrics and director of the Center for Childhood Infections & Vaccines at Emory, says: “AZD5582 was remarkable in its ability to reactivate latent SIV from resting CD4+ T cells, and to induce continued virus production in the blood when monkeys were still receiving daily antiretroviral therapy.”
A team of scientists from the US National Institutes of Health and the pharmaceutical company Sanofi developed an antibody able to attack 99% of HIV strains and can prevent infection in primates. Human trials believed to start in 2018 in order to see if it can prevent or treat an infection.
This development combined three antibodies into a more powerful try-specific antibody.
Dr Gary Nabel, the chief scientific officer at Sanofi and one of the report authors, explains: “They are more potent and have greater breadth than any single naturally occurring antibody that’s been discovered. We’re getting 99% coverage, and getting coverage at very low concentrations of the antibody.”
Chinese specialists are going to actively include traditional Chinese medicine in the treatment of AIDS, doubling the number of patients who will test a new approach. As the Business Standard journal reports, chinese experts are discussing an implementing a five-year project of learning ancient medical practices.
However, this does not mean that Chinese experts want to abandon standard antiretroviral therapy. They are betting on the merger of the West and the East. Moreover, according to officials, the involvement of traditional therapy techniques will significantly save money, without resorting to expensive high-tech care.
The new strategy, according to Chinese experts, will make it possible to reduce the level of infection among homosexual individuals by at least 10%, and mother to child transmission rates to less than 4%.
Toxins of tropical frogs can become an indispensable tool for fighting AIDS and cancer. Experiments have shown that small doses of a dangerous substance has healing properties.
Panamanian researchers conducted a series of studies aimed to understand the effects of toxic substances, which allocated by the body of toads. The substance, which is produced by the skin of amphibians, can hurt the animal itself, and even cause paralysis.
Experiments have demonstrated that low doses of the toxin has a positive effect on human’s organism. First of all, its effective as an analgesic remedy. In addition, substances own the properties that influence the rhythm of heart. It is possible that its destructive properties work for the destruction of cancer cells and the AIDS virus.
A team of scientists from Israel has developed a new substance that can kill virus cells without damage to healthy cells and the organism as a whole. Currently, the drug is still undergoing laboratory tests, so it’s early to speak about the mass use yet.
The developed material was mixed in the tubes with contaminated blood. The blood was taken from patients who are currently being treated in hospital Kaplan. Thus, clinicians have found that only in 8 days the number of “sick” cells decreased by 97%. At the same time, it was well established that healthy cells are not affected at all.
The head of a group of scientists who worked on the creation of this product Loiter Abraham told that the drug contains a special peptide. This material makes multiple copies of DNA of the disease in the affected cell. As a result, the cells begin a self-destruction. There is only the destruction of infected organisms. In addition, there is no chance that the virus can re-start the development, since the cells are destroyed completely.
Also, scientists have noted that the drug may exacerbate some of the processes in the body of the patient, which significantly increases the likelihood of infected cell death. If the drug shows its best side during further tests, it will be used for the treatment. However, scientists can not say when it will be exactly, because there is still a lot of work.
It should be noted that every year the number of people infected with AIDS is increasing. Doctors strongly recommend to take precautions in a timely manner to be tested and pass inspection. In this case, prevention is the only effective mean.