Heavy Alcohol Consumption Connected to Chemical Changes in Genes

heavy drinking linked to chemical changes in genes

A new study, conducted by researchers from Rutgers University, finds chemical changes in two significant genes with heavy and binge drinking adults.

For the study, two genes, hypothalamic proopiomelanocortin (POMC) and Per2, were analyzed in blood samples taken from 47 volunteers who participated in larger experiment on drinking behaviors. The group of volunteers included non-smoking moderate consumers, alcohol bingers, or heavy drinkers.

The analysis showed that there is a tendency for Per2 and POMC genes among binge- and heavy drinkers to be methylated. This process of gumming up a gene with a molecule is described as an epigenetic change. The gene’s code remains the same, but its expression is altered. In this case, the methylation forced the genes to decrease their expression.

Physical Activity May Restrain Harmful Effects of Alcohol Consumption

Meeting the recommended amount of physical activity may offset some of the cancer and all-cause mortality risk connected to alcohol consumption, a study published in the British Journal of Sports Medicine suggests.alcohol consumption

In their survey, the team of researchers included data from the responses to nationally representative health surveys in England and Scotland, where each was linked to cause-specific mortality, for the years 1994, 1998, 1999, 2003, 2004, and 2006.

Having analyzed the given data, scientists concluded that the risk of death had increased or decreased depending on the level of physical activity.

People were more likely to die from cancer and alcohol intake rose from within the recommended limits up to harmful levels and they didn’t meet the minimum recommended levels of 7.5 MET/hour (Metabolic Equivalent of Task).

More details here.

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