In a new study from Denmark, researchers found that regular exposure to traffic noise may increase the risk of developing all-cause dementia, and Alzheimer’s disease in particular.
The current study included almost 2 million adults, aged 60 years and over, who lived in Denmark between 2004 and 2017. The scientists examined exposure to road traffic and railway noise for all participants’ residential addresses and taking into consideration the buildings’ most and least exposed sides.
The researchers used high-quality national health registers of Denmark to find cases of all-cause dementia and other types of dementia reported during the period of 8.5 years. These conditions included Alzheimer’s disease, vascular dementia, and Parkinson’s disease.
The analysis of the gathered data showed that over 103,000 new cases of dementia occurred during this period, and noise from road traffic and railways is associated with a higher risk of all forms of dementia.
Scientists from the Salk Institute, US, found that a drug candidate that previously slowed aging in brain cells was also able to successfully reverse memory loss in a mouse model with the inherited Alzheimer’s disease.
For the last few decades, this team of researchers studied a chemical named fisetin, found in fruits and vegetables. They developed a version of the chemical called CMS121 which proved to be effective in slowing the loss of brain cells.
Now, the researchers evaluated the effect of CMS121 on the mouse model. The results of the experiment showed that mice with Alzheimer’s-like disease that received the chemical showed equal performance as healthy control mice in memory and behavior tests.
A new laboratory study, conducted by researchers from Lancaster University in the United Kingdom, finds that the asthma drug salbutamol prevents the formation of tangles of fibrous protein that are a hallmark of Alzheimer’s disease.
For the study, scientists screened more than 80 compounds for their ability to block the formation of tangles with the help of a powerful technique called synchrotron radiation circular dichroism.
Lead study author Dr. David Townsend says: “Salbutamol has already undergone extensive human safety reviews, and if follow-up research reveals an ability to impede Alzheimer’s disease progression in cellular and animal models, this drug could offer a step forward, whilst drastically reducing the cost and time associated with typical drug development.”
According to a new study, completed by scientists from the Keck School of Medicine at the University of Southern California in Los Angeles, US, air pollution may affect the mental health: tiny polluting particles may possibly enter the brain.
For this research, a team of scientists analyzed data from 998 women whose aged was from 73 to 87 taken from the Women’s Health Initiative (US). Within the program, up to two brain scans were performed for each participant.
The analysis of the received data showed that the higher a person’s exposure to fine particle pollution, the higher the risk of this person to experience cognitive function impairments like problems with memory.
Study co-author Andrew Petkus says: “This study provides another piece of the Alzheimer’s disease puzzle by identifying some of the brain changes linking air pollution and memory decline. Each research study gets us one step closer to solving the Alzheimer’s disease epidemic.”
A new study from the United States finds that certain nutrients in a mother’s diet may reduce the influence of the Alzheimer’s disease on offspring.
study, researchers bred mice, genetically predisposed to Alzheimer’s disease
from females whose diet was high in choline, a compound similar to B vitamin
group which can be found in liver, meat, fish, nuts, spinach, eggs, peas,
beans, wheat germ.
Having performed the examination, the scientists discovered that offspring of the females with choline-rich diet showed fewer condition-associated brain changes and improved cognitive performance compared to offspring of non-supplemented mice.
Lead study author Dr. Ramon Velazquez of the Biodesign Institute at ASU comments: “Choline deficits are associated with failure in developing fetuses to fully meet expected milestones like walking and babbling.