Recent research, presented at the European Society for Medical Oncology World Congress on Gastrointestinal Cancer 2021, suggests that people, especially those who are 50 years and over, may have a higher risk of colorectal cancer due to overuse of antibiotics.
For the study, a team of scientists analyzed data of a total of 7,903 individuals with colorectal cancer, comparing them with the data of 30,418 individuals without the condition. Of the study participants diagnosed with colorectal cancers, 445 were under the age of 50.
The analysis showed that there is a link between antibiotic use and a higher risk of colorectal cancer. The researchers also noted that individuals with later-onset colorectal cancer had an associated risk of 9%. The association was significantly higher in those with early-onset colorectal cancer, with an almost 50% increased risk.
According to recent research, which appeared in the journal Microbial Biotechnology, there is an association between heavy metal and radioactive soil pollution and the antibiotic resistance of bacteria in the soil.
Scientists believe that bacteria become resistant to antibiotics due to their improper or indiscriminate use. For instance, this phenomenon happens due to the widespread use of antibiotics in farms, regardless of whether the animals have a bacterial infection or not.
Corresponding study author Jesse C. Thomas IV comments: “The overuse of antibiotics in the environment adds additional selection pressure on microorganisms that accelerates their ability to resist multiple classes of antibiotics. But antibiotics aren’t the only source of selection pressure. Many bacteria possess genes that simultaneously work on multiple compounds that would be toxic to the cell, and this includes metals.”
According to the latest study, published in the European Journal of Public Health, regular use of probiotics may cut the necessity for antibiotics and help decrease the rise of antibiotic resistance.
Having performed the analysis of the data, collected from recent studies, the researchers came to the conclusion that infants and children who took a daily probiotic supplement were 29% less likely to be prescribed antibiotics. When analyzed only the highest-quality study, the scientists received even higher figure 53%.
Dr. Daniel Merenstein, from the Department of Family Medicine at Georgetown University School of Medicine in Washington D.C., says: “Given this finding, potentially one way to reduce the use of antibiotics is to use probiotics on a regular basis.”
A new study from the University of Salford, UK, suggests that a combination of vitamin C and antibiotics can destroy cancer stem cells. This discovery can help develop a new strategy to fight cancer recurrence and treatment resistance.
In the course of the study, a team of researchers combined doxycycline administration with doses of vitamin C and was able to remove glucose from CSCs that effectively starved the cells to death.
Professor Michael Lisanti says: “Our results indicate it is a promising agent for clinical trials, and as an add-on to more conventional therapies, to prevent tumor recurrence, further disease progression, and metastasis.”
A team of researchers from McGill University discovered that maple syrup extract can decrease the usage of antibiotic by improving the potentiality of the medicine.
At the first stage of the study, lead researcher Natalie Tufenkji separated the sugar and water from the syrup’s phenolic compounds and exposed with several bacterial strains that cause various disease. However, she didn’t find any noticeable changes. But when she mixed the phenolic extract with commonly used antibiotics then the antimicrobial potency hiked up.
Dr. Tufenkji explained that the syrup extract actually increases the permeability of bacteria that helps antibiotics to gain access to the interior of cells.