Vitamin C May Prevent Blood Cancer Stem Cells from Growing

A new study, conducted by researchers at the Perlmutter Cancer Center at New York University Langone Health in New York City, demonstrated how vitamin C might stop blood cancer stem cells from multiplying. That helps block some forms of leukemia from advancing.blood cancer stem cells

Scientists discovered that intravenous treatment with vitamin C promoted DNA demethylation, making cancer stem cells to mature and die. This treatment also stopped blood cancer stem cells that were transplanted from human patients to mice from growing.

Corresponding study author Benjamin Neel, Ph.D., director of the Perlmutter Cancer Center, says: “Our results suggest that high-dose vitamin C – and it’s important to note that this means disease that has to be administered [intravenously] – might have therapeutic benefit in TET2-mutant myelodysplastic syndrome, either alone or in combination with current demethylating therapies and/or PARP inhibitors.”

Aggressive Blood Cancer Is Not One But 11 Distinct Diseases

A study, published in the New England Journal of Medicine, suggests that some patients respond to blood cancer treatment better than others due to the genetic differences. According to the detailed genetic analysis, one of the main types of blood cancer is not one but eleven distinct diseases.blood cancer

The study focused on acute myeloid leukaemia (AML), which is often aggressive, especially in older patients. Overall survival rate after 5 years is about 20%.

The team of researchers examined more than 100 genes known to cause leukaemia and investigated how they interacted.

The scientists believe that their findings can help with the development of corresponding clinical trials of blood cancer.

Dr. Áine McCarthy from Cancer Research UK said: “Science such as this continues to offer new insights into cancer which can help us achieve our goal of beating the disease.”

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