Severe forms of childhood epilepsy, which are not amenable to standard therapy with anticonvulsants may be cured with the new experimental drug based on purified cannabidiol. The drug has a working title Epidiolex.
In the third phase of clinical tests, the drug was given to 61 patients at a dosage of 20 milligrams per kilogram of body weight. There was also a control group of 59 patients. The average age of the volunteers was 10 years and about 30% of patients were younger than 6 years. Together with the experimental drug children continued to receive standard anticonvulsant drugs.
Scientists say that Epidiolex helped to reduce the monthly frequency of seizures by 39%. In placebo background frequency of attacks has fallen by only 13%. The main ingredient of the drug – purified cannabidiol. What is important, there is no THC, the main psychoactive compound of marijuana. If the drug is registered, it will be a real breakthrough. Annual sales could exceed $ 1.1 billion by 2021.