A new study in mice, conducted by the researchers from Xuzhou Medical University in China, suggests that resveratrol, a red wine compound, can be used for the treatment of depression and anxiety in the future.
In this study, the scientists used animal models and cultured mouse neurons (similar to those in the human hippocampus) to help explain the effect of the compound on rodent behaviors.
Resveratrol, which appears to reduce anxiety and depression in mice, seems to work by inhibiting PDE4D (a member of the PDE4 family that believed to be particularly important in cognition and depression) and activating cAMP (cyclic adenosine monophosphate) signaling.
Co-lead author Dr. Ying Xu, Ph.D. says: “Resveratrol may be an effective alternative to drugs for treating patients suffering from depression and anxiety disorders.”
A new study from Taiwan suggests that the use of antidepressant therapies may decrease the number of deaths by 35% in patients suffering from diabetes and depression.
For their research, the scientists used the Taiwan National Health Insurance Research Database, where they identified 53,412 individuals, of which 50,532 were taking antidepressants and 2880 people took no antidepressants.
The data showed that among the patients in the non-antidepressant group the rate of heart failure, the rate of heart failure was higher but no significant differences were detected between groups in regard to the other 3 comorbid chronic diseases.
The incidence rate of deaths events ranged from 1113.7 (95 %CI: 1078.4-1150.3) per 100,000 person-years in the highest group to 1963.7 (95%CI: 1876.8-2054.7) per 100,000 person-years in the lowest group. Researchers noted that the rates of death decreased as the total cumulative dose increased.
A new study from the Hellenic Open University in Patra, Greece, finds a link between consuming products of the Mediterranean diet and lower risk of depression.
For the study, a team of researchers used data received from members of day-care centers for senior people in the East Attica region in Greece. Among the participants, 64 percent moderately adhered to the mentioned diet and 34 percent highly adhered to the diet.
Having analyzed the received data, the scientists found that participants with higher adherence to the Mediterranean-type diets, especially those who ate more vegetables, less poultry, and drank less alcohol, showed a lower probability of developing depression or depression symptoms.
Study authors note in their paper: “Our results support that depression in older adults is common and strongly associated with several risk factors.”
The researchers used an adapted version of a mood induction task called the Trier-Social Stress Task, intended to cause feelings of stress and anxiety in the subject. During the study, 71 children aged 3 and 8 were asked to tell a short story within 3 minutes. They were told that they would be judged based on how interesting it was.
To analyze children’s speech, scientists used a machine learning algorithm. The algorithm proved to be very successful at diagnosing children.
Study senior author Ryan McGinnis says: “The algorithm was able to identify children with a diagnosis of an internalizing disorder with 80% accuracy, and in most cases that compared really well to the accuracy of the parent checklist.”
A new study from Sweden finds that obesity in youth increases their risk of anxiety and depression.
In the course of study, a team of researchers analyzed data from over 12,000 children and teenagers aged from 6 to 17 who were treated from obesity. These data have been compared with the data from 60,000 kids and teens without obesity.
The scientists concluded in their paper that the girls with obesity were 43 percent more likely to have anxiety or depression compared with their age- and sex-matched counterparts. The risk of anxiety and depression was also 33 percent higher among boys with obesity, compared with their peers without obesity.