A new study from Denmark shows that such widespread painkiller as ibuprofen can have a significant negative effect on male fertility affecting testicular health, altering hormone production and inducing compensated hypogonadism.
For the research, the scientists recruited 31 men aged between 18 and 35 half of whom received a moderate dose (600 mg, or three tablets) of the drug daily during six weeks. The other group received placebo. Within 2 weeks, the men who were taking ibuprofen on a daily basis demonstrated an increase in luteinizing hormones.
The team writes in their paper: “It is also of concern that men with compensated hypogonadism may eventually progress to overt primary hypogonadism, which is characterized by low-circulating testosterone and prevalent symptoms including reduced libido, reduced muscle mass and strength, and depressed mood and fatigue.”