Pomegranate May Help in Treatment of Inflammatory Bowel Disease

Researchers from the University of Louisville in Kentucky suggest that natural polyphenols found in pomegranate can fight symptoms of inflammatory bowel disease (IBD). Polyphenols are also present in berries such as strawberries, blackberries, and raspberries.

The scientists found a metabolite named urolithin A (UroA) is produces as a result of polyphenols in fruits and gut bacteria interacting. Using animal model, the researchers demonstrated UroA and UAS03 increase proteins that tighten epithelial cell junctions in the gut.

The first study author Dr Rajbir Singh comments: “The general belief thus far in the field is that urolithins [such as UroA and UAS03] exert beneficial effects through their anti-inflammatory, anti-oxidative properties. We have for the first time discovered that their mode of function also includes repairing the gut barrier dysfunction and maintaining barrier integrity.”

Strawberries Could Help Reduce Harmful Inflammation in Colon

A new study, executed by the researchers from the University of Massachusetts Amherst, suggests that eating less than a cup of strawberries on a daily basis may help reduce harmful inflammation in the colon and improve the symptoms of inflammatory bowel disease (IBD).strawberries reduce harmful inflammation

For the research, the scientists used a mice model having split the mice into four groups. Having performed analysis of the received data, the researcher concluded that eating the equivalent of three-quarters of a cup of strawberries each day reduced weight loss and symptoms of IBD such as bloody diarrhea.

In addition, the mice that consumed strawberries showed the reduced levels of harmful gut bacteria, such as Akkermansia and Dorea, and higher levels of healthy flora, such as Lactobacillus and Bifidobacterium.

Living in a Rural Area Linked to Lower Risk of Inflammatory Bowel Disease

A new Canadian study, published in The American Journal of Gastroenterology, suggests that people living in a rural area are less likely to develop inflammatory bowel disease (IBD) compared to people living in urban areas.rural area linked to a lower risk of bowel disease

The researchers analyzed dozens of studies and found a link between increased urbanization and a greater number of IBD cases. The results are full of inconsistencies, but this can be explained due to many differences in rural areas.

Dr. Eric Benchimol, a pediatric gastroenterologist at the CHEO Inflammatory Bowel Disease Center, says: “We’ve known that in addition to genetic risk factors, environmental factors have been associated with the risk of developing IBD. But this new study demonstrated the importance of early life exposure in altering the risk of IBD, and that needs further study.”