Scientists from the University of Edinburgh found that smoking cannabis have reduced bone density and caused fractures in heavy cannabis users. The study also found that heavy cannabis smokers have lower body weight and body mass index (BMI) and that contributes to thinner bones in their bodies.
For their study, the team of researchers assessed 170 people who smoke cannabis regularly. They found that the bone density of heavy cannabis users was about 5% lower than regular cigarette smokers.
Professor Stuart Ralston, a lead researcher from the University of Edinburgh’s Centre for Genomic and Experimental Medicine says: “We have known for a while that components of cannabis can affect bone cells function but we had no idea up until now of what this mean to people who use cannabis on a regular basis.”
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Severe forms of childhood epilepsy, which are not amenable to standard therapy with anticonvulsants may be cured with the new experimental drug based on purified cannabidiol. The drug has a working title Epidiolex.
In the third phase of clinical tests, the drug was given to 61 patients at a dosage of 20 milligrams per kilogram of body weight. There was also a control group of 59 patients. The average age of the volunteers was 10 years and about 30% of patients were younger than 6 years. Together with the experimental drug children continued to receive standard anticonvulsant drugs.
Scientists say that Epidiolex helped to reduce the monthly frequency of seizures by 39%. In placebo background frequency of attacks has fallen by only 13%. The main ingredient of the drug – purified cannabidiol. What is important, there is no THC, the main psychoactive compound of marijuana. If the drug is registered, it will be a real breakthrough. Annual sales could exceed $ 1.1 billion by 2021.