A team of researchers from Columbia University Medical Center found a common genetic variant that significantly affects normal brain aging in senior adults, beginning at about age 65, and able to change the risk for neurodegenerative diseases.
For the study, the researchers analyzed genetic data from autopsied human brain samples taken from 1,904 people without a neurodegenerative disease. Then they compared these data to the average transcriptome of people of the same age looking at 100 genes whose expression was found to increase or decrease with aging. Using this method, the scientists managed to identify the variant TMEM106B. About 1/3 of people have two copies and another 1/3 have one copy.
Researchers believe that these findings could point toward a new biomarker for the evaluation of anti-aging interventions and help find new ways of prevention or treatment of such age-associated disorders as Alzheimer’s disease.
A new research, executed by the scientists from the Harvard-affiliated Hebrew Senior Life and the University of Massachusetts, shows that a combination of vitamin D supplements and certain dairies can protect seniors from age-related bone loss.
The study included participants who have been enrolled in the long-term Framingham Study, which began in 1948. The study followed the health and habits of residents of the town of Framingham, Massachusetts, USA.
The lead author Shivani Sahni of the study says that it is significant because it looked at dairy products other than just milk, and it also clarified that the association of dairy foods with bone density is dependent on adequate vitamin D intake.
A new study confirms that aerobic exercise not only increases brain size (as previous research suggested), but also can improve cognition in senior patients with mild cognitive impairment (MCI).
For the study, the researchers examined 35 adults with MCI. The participants were divided in two groups: one group included 16 adults with average age 63, another group was a control group including 19 adults with average age 67.
The first group performed a range of aerobic activities such as treadmill, cycling, and elliptical training. They had training sessions 4 times a week during 6 months. The control group performed stretching exercises with the same schedule.
At the end of the 6-months period, the scientists found that those who performed aerobic exercising had improved more significantly compared to the stretching group.
More information about the study is here.