Vitamin C May Prevent Blood Cancer Stem Cells from Growing

A new study, conducted by researchers at the Perlmutter Cancer Center at New York University Langone Health in New York City, demonstrated how vitamin C might stop blood cancer stem cells from multiplying. That helps block some forms of leukemia from advancing.blood cancer stem cells

Scientists discovered that intravenous treatment with vitamin C promoted DNA demethylation, making cancer stem cells to mature and die. This treatment also stopped blood cancer stem cells that were transplanted from human patients to mice from growing.

Corresponding study author Benjamin Neel, Ph.D., director of the Perlmutter Cancer Center, says: “Our results suggest that high-dose vitamin C – and it’s important to note that this means disease that has to be administered [intravenously] – might have therapeutic benefit in TET2-mutant myelodysplastic syndrome, either alone or in combination with current demethylating therapies and/or PARP inhibitors.”

Combination of Vitamin C and Antibiotics Can Kill Cancer Stem Cells

A new study from the University of Salford, UK, suggests that a combination of vitamin C and antibiotics can destroy cancer stem cells. This discovery can help develop a new strategy to fight cancer recurrence and treatment resistance.vitamin c kills cancer stem cells

In the course of the study, a team of researchers combined doxycycline administration with doses of vitamin C and was able to remove glucose from CSCs that effectively starved the cells to death.

Professor Michael Lisanti says: “Our results indicate it is a promising agent for clinical trials, and as an add-on to more conventional therapies, to prevent tumor recurrence, further disease progression, and metastasis.”